Who really means business in Serie A – Milan or Juventus?Both giants endured turbulent campaigns last season and failed to qualify for the Champions League. Milan parted ways with Massimiliano Allegri and turned to Ruben Amorim, while Luciano Spalletti remained in charge of Juventus.With Inter still looking like the team to beat, Roma making a perfect start and Como quietly emerging as another contender, tonight's heavyweight clash (9.45 pm) could provide the first real indication of where Milan and Juventus stand.##NAJAVA_MECA_9936891##Lautaro at the death! Martinez's brace kills Napoli to seal a stunning comebackBoth sides have won their opening two matches, but the Bianconeri have the better defensive record, with Spalletti's men yet to concede.The two clubs have also undergone major changes, particularly in attack. Milan have lost Rafael Leao to Galatasaray, with his compatriot Goncalo Ramos, signed from European champions Paris Saint-Germain, now expected to lead the line.Juventus have also completely reshaped their frontline. Jonathan David, Lois Openda and Dusan Vlahovic have all left Turin, while Randal Kolo Muani has returned and could become the focal point of Spalletti's attack.Crazy, crazier, Serie A: Roma produce stunning late comeback to sink AtalantaThe Juventus boss, however, has plenty of problems to solve before the San Siro trip. He will be without eight players: Khephren Thuram, Kenan Yildiz, Jeff Ekatour, Juan Cabal, Weston McKennie, Andrea Cambiaso, Pape Matar Sarr and Arkadiusz Milik."We have difficulties because many players are injured, but their problems are all different. We started the season well, but we have to improve because Milan are very aggressive in their pressing," Spalletti said.Milan have far fewer selection concerns, with Matteo Gabbia their only absentee. Serbian international Strahinja Pavlovic is expected to anchor the defence, having remained a key figure under Allegri and his predecessor Sergio Conceicao.BETTING GUIDE: Juventus vs AC Milan, match preview, team news and predictionAmorim is delighted with the work done in the transfer market and believes Milan now have the squad to compete."Every player we signed is perfect for our team, so I'll give the transfer window a 10. I have the best team in the world," the Portuguese coach said confidently.By the final whistle, Serie A may have its first real clue as to which of these two giants is ready to challenge the early favourites.SERIE A – MATCHDAY 3FridayGenoa – Como 1-4 (1-3)/Osmajic 19 – Baturina 25, Diao 30, 78, Paz 40SaturdayFiorentina – Torino 1-2 (0-0)/Pellegrino 47 – Mandragora 74, Adams 82/Inter – Napoli 3-2 (0-0)/Lautaro 56, 90+1, Thuram 82 – Politano 50, Hojlund 53/Roma – Atalanta 2-1 (0-0)/Hermoso 89, Soule 90+2 – Ederson 47/Sunday17.00: (2.75) Frosinone (3.25) Venezia (2.65) 17.00: (2.55) Parma (3.15) Monza (2.95) 20.00: (2.05) Bologna (3.40) Sassuolo (3.70) 22.45: (2.15) Juventus (3.45) Milan (3.70)Monday20.30: (1.97) Cagliari (3.35) Lecce (4.10) 22.45: (2.95) Udinese (3.15) Lazio (2.55) ***odds are subject to change***