Big-spending Tottenham endured a nightmare opening to their new Premier League campaign, suffering a heavy defeat against an energetic Brentford side at the Gtech Community Stadium.Spurs have invested around £237m during the summer, breaking their transfer record twice as they look to put last season's struggles behind them, when their Premier League survival was only secured on the final day.Four new arrivals were handed starts in west London, with Andy Robertson, Marcos Senesi, Jan Paul van Hecke and club-record signing Sandro Tonali all included in the starting XI.Defeat on the opening day. pic.twitter.com/QXZJm62Tsv— Tottenham Hotspur (@SpursOfficial) August 22, 2026 However, Tottenham quickly found themselves in serious trouble. Brentford took the lead in the 12th minute when Lewis-Potter was left completely unmarked inside the penalty area and made no mistake after being picked out by the Bees' record summer signing, Sangare.GOAL! Lewis-Potter fires a low shot into the net as Sangare assists! Brentford 1-0 Tottenham pic.twitter.com/5hlkhpJuwd— DaKingLamar Sports Hub (@dakinglamar007) August 22, 2026 Sangare was at the heart of almost everything Brentford did well as the hosts continued to dominate. Their pressure eventually paid off again in the 33rd minute, when Janelt followed up to score from close range after Antonin Kinsky had denied Jensen.GOAL! Janelt pounces on the rebound inside the box and rifles the ball home! Brentford 2-0 Tottenham pic.twitter.com/2ffjmqnPVp— DaKingLamar Sports Hub (@dakinglamar007) August 22, 2026 Tottenham were unable to respond before the interval and failed to produce a single shot on target during a hugely disappointing first half.Roberto de Zerbi reacted immediately after the restart, introducing £85m signing Mateus Fernandes and Bentancur in place of Gallagher and Bergvall.The changes did little to alter the course of the match, however, as Brentford extended their advantage. In the second half, Michael Kayode found the net after the ball fell kindly to him following a save from Kinsky, with Sangare's effort having initially been kept out.GOAL! Brentford 3-0 Tottenham pic.twitter.com/DclEn1YViM— DaKingLamar Sports Hub (@dakinglamar007) August 22, 2026 Things almost got even worse for Spurs when Bentancur brought down Kevin Schade inside the area, prompting referee Michael Oliver to award Brentford a penalty. Igor Thiago stepped up, but his spot-kick struck the post and bounced away after Kinsky had committed himself in the opposite direction.That miss ultimately mattered little, with Brentford comfortably seeing out the remainder of the contest. Tottenham were thoroughly outplayed by a sharp, energetic and clinical home side, making their opening-day defeat a particularly worrying start given the scale of their summer spending.PREMIER LEAGUE – MATCHDAY 1FridayArsenal – Coventry 3-0 (2-0)/Havertz 15, Saka 23, Odegaard 49/SaturdayHull – Manchester United 2-0 (2-0)/Ajayi 17, Mendy 38/Everton – Crystal Palace 2-0 (1-0)/Dewsbury-Hall 42, Barry 53/Ipswich – Sunderland 2-1 (1-1)/Emersonn 24, Clarke 90 – Angulo 39/Nottingham Forest – Leeds 0-1 (0-0)/Stach 88/Brentford – Tottenham 3-0 (2-0)/Lewis-Potter 12, Janelt 33, Kayode 49/Sunday16.00: (2.30) Brighton (3.50) Aston Villa (3.25)16.00: (1.53) Manchester City (5.00) Bournemouth (6.00)18.30: (3.90) Newcastle (3.70) Liverpool (2.00)Monday22.00: (3.70) Fulham (3.80) Chelsea (2.00)***odds are subject to change***